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Upcoming Events at the San Diego Chapter

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TUESDAY, MARCH 14, 2006
The San Diego Chapter of the Licensing Executives Society
Panel Discussion Featuring:
"Specialty Pharmaceuticals -- Licensing & IP Strategies for Faster Value Creation"
Sponsored by:
Knobbe Martens Olson & Bear LLP

SPEAKERS:

Laurent Fischer, President & CEO of Ocera Therapeutics 
Bob More, Partner  Domain Associates 
Karen Dow, Partner  Townsend and Townsend and Crew LLP
Richard K. Masterson, Jr.  VP, Global Commercial  Development  Valeant  Pharmaceuticals  International

Moderator:
David Palella, President, BioScience Ventures, Inc.

PROGRAM DESCRIPTION:
Specialty Pharma companies rescued the San Diego life science VC community from the post-NASDAQ bubble's "Slough of Despond".  Funds' entire IRR (internal rate of return) often resulted from successful exits (usually via M & A) from only 1 or 2 specialty pharma companies in a portfolio. Specialty Pharma was the business model du jour, a seemingly inexhaustible venture investor's ATM.  Local specialty pharma M & A exits of note include Elan's acquisition of Dura; Valeant's of Xcel Pharmaceuticals; and Cephalon's of Salmedix.

But the Specialty Pharma business model is entering middle age -- graying at the edges, becoming myopic and pining for trophy products!  Initially based on product arbitrage, rapid clinical development and a refined sales/marketing focus, "success" now requires private equity investors with tons of cash and extreme product make-overs yielding often cosmetic differential  advantages in the marketplace.

So what's the next step for the model?  Backward integration towards R&D? Lateral expansion into two or more therapeutic areas?  More drug delivery system (DDS) platform companies morphing into Specialty Pharma companies? Building a bigger financial sledgehammer a la Jazz Pharmaceuticals?  Tune in to this panel for the next episode of "As the Specialty Pharma World Turns"!

PANELISTS BIOGRAPHYS:

Laurent Fischer, M.D., President and CEO
Dr. Fischer is the co-founder of Ocera, he has more than  15 years of drug development and commercial experience in the  biopharmaceutical industry and has raised over $25M in venture financing.  He was involved in the start-up of four healthcare ventures, and has an  extensive background in drug development, medical affairs, sales and  marketing.

Previously, Dr. Fischer was president and CEO of Auxeris  Therapeutics, a biotechnology company developing RANKL inhibitors. Dr. Fischer was senior vice president of the global virology business at DuPont-Merck and DuPont Pharmaceuticals and launched  Sustiva™ worldwide ($750M in annual sales). DuPont Pharmaceuticals was sold to Bristol Myers Squibb for $7.6 billion in 2001.  He also worked on the development of several drugs and new indications at  Hoffmann-La Roche in the area of cancer and infectious disease and was  medical director for Roche in the U.S. where he launched the first  protease inhibitor, Invirase™, and developed the second-generation,  Fortovase™ for the treatment of HIV.

Dr. Fischer received his undergraduate degree from the University of Geneva and his medical degree from the Geneva Medical School, Switzerland.  He serves on the board of directors of the AIDS Healthcare Foundation, the world’s largest specialized provider  of AIDS care.

Robert J. More, Partner
Mr. More joined Domain Associates as a Kauffman Fellow in 1996, and he became a General Partner in 2000.  Since joining Domain, Bob has served on the Board of Directors of ESP Pharma, Proxima Therapeutics, Onux Medical, and was responsible for Domain’s investment in IntraLase. Currently, he serves on the Boards of Glaukos, OmniSonics Medical Technologies, Novalar Pharmaceuticals, NovaCardia, TargetRx, Receptor Biologix, and Esprit Pharma.

From 1997-1998, he served as the Chief Operating Officer of Small Molecule Therapeutics, a Domain portfolio company subsequently purchased by Morphochem AG. From 1992 to 1995, Bob was in sales with Pharmacia.

Prior to joining Pharmacia, he held a research position at Somatogen, a start-up company developing a recombinant blood substitute that was subsequently purchased by Baxter.

Education:

- B.A. - Middlebury College, 1989
- M.B.A. - Darden School of Business Administration, University of Virginia, 1996

Karen B. Dow
Karen B. Dow, Partner-in-Charge of Townsend and Townsend and Crew’s San Diego office, is one of the pioneers in biotechnology patent law. She has more than 20 years of patent experience in life science corporations and law firms and has served as principal outside patent counsel to numerous biotechnology and pharmaceutical companies.

Ms. Dow specializes in providing counsel and advice to clients to obtain, protect and enforce their intellectual property rights, particularly in the areas of immunology, molecular biology, bioinformatics, bioarray technology, microbiology, pharmaceuticals, vaccines, diagnostics, organic chemistry, and the emerging field of stem cell research. She has extensive experience in intellectual property transactions, patent interferences, due diligence investigations, public offerings, oppositions, and regularly obtains patents for clients in the United States and abroad.

Ms. Dow brings unique perspective to complex intellectual property issues, combining her experience as an attorney with major pharmaceutical and biotechnology companies with her knowledge as a prominent figure at law firms. She began her career as a patent attorney at Eli Lilly and then joined Triton Biosciences as a senior patent and licensing attorney. Subsequently, she was a partner in Townsend's Palo Alto office, and a partner at a law firm in San Diego, where she was co-chair of the firm-wide Life Sciences Group.

Ms. Dow has lectured extensively in the areas of patent law and intellectual property transaction law, and has been a guest lecturer for the University of California intellectual property extension classes. She has been a guest speaker for an array of organizations, ranging from American Women in Science to the California Bar Association.

In 2005, Ms. Dow was named by the San Diego Daily Transcript as one of the Top 10 intellectual property attorneys in San Diego. In 2004, she was nominated for the Athena Pinnacle Award, Individual in Technology, and was featured on Forbes SkyRadio for American Airlines, addressing patent issues in biotechnology. In 2002, she was profiled in, and appeared on the cover of, San Diego Lawyer Magazine.

She received her bachelor’s degree from Bowling Green State University and her J.D. from Indiana University.

Richard K. Masterson
Richard K. Masterson, joined Valeant in 2004 as Vice President, Global Commercial Development, responsible for worldwide marketing and business development at this $800M specialty pharmaceutical company.

Prior to joining Valeant Rich spent fifteen years at TAP Pharmaceutical Products in Chicago.  His last assignment at TAP was as Vice President and General Manager, Lupron, where he was responsible for a $900m specialty business in gynecology and urology. Prior to managing the Lupron business, Rich was TAP’s Vice President of Licensing, where he completed a wide range of licensing and co-promotion deals in a variety of therapeutic areas.  Rich joined TAP in 1989 and held a number of positions in sales, and marketing before joining the licensing department.

Before TAP, Rich was a Lieutenant in Special Operations in the U.S. Navy.  He holds a BA in Economics from the University of Virginia and a Masters of Business Administration from the J.L. Kellogg Graduate School of Management at Northwestern University.  He is married with two children and resides in Irvine, CA.

For additional information, please contact:
Ross A. Epstein, Chair
Tel.  (858) 792-8211
Fax  (858) 792-8946
e-mail: repstein@nathlaw.com

or

Kasia A. Epstein, Event Coordinator
Tel. (619) 944-1628
e-mail: Kasia-Epstein@sbcglobal.net

 



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